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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Dermatofibrosarcoma protuberans diagnosed by a single biopsy.

Kristian Bakke Arvesen¹, Carsten Sauer Mikkelsen¹, Torben Steiniche²

¹Dermatology Clinic, Brønderslev;

Dermatology Reports

|November 12, 2014

Summary

A biopsy confirmed dermatofibrosarcoma protuberans in a 9-year-old girl with a thigh lesion. Surgical resection achieved clear margins, with no signs of metastasis detected.

Keywords:

biopsy.dermatofibrosarcoma protuberans thigh

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Area of Science:

Dermatology
Pediatric Oncology
Surgical Pathology

Background:

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing malignant skin tumor.
Early diagnosis and complete surgical excision are crucial for optimal patient outcomes.
Pediatric DFSP is exceptionally rare, necessitating careful diagnostic evaluation.

Observation:

A 9-year-old female presented with a 2.5 cm circular, blue-to-violet discoloration on her left anterolateral upper thigh.
Initial clinical presentation raised suspicion for a neoplastic process.

Findings:

A biopsy confirmed the diagnosis of dermatofibrosarcoma protuberans.
Surgical resection at a specialized sarcoma center resulted in wide, clear resection margins.
Preoperative chest X-ray indicated no evidence of metastatic disease.

Implications:

This case highlights the critical role of biopsy in diagnosing ambiguous cutaneous lesions, especially in pediatric patients.
Prompt surgical intervention with adequate margins is effective in managing localized DFSP.
The absence of metastasis suggests a favorable prognosis for this pediatric case, underscoring the importance of early detection.