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Embryonal/Fetal subtype hepatoblastoma: a case report
I Spyridakis1, C Kepertis2, V Lampropoulos2
1Assistant Professor, Department of Paediatric Surgery, Aristotle University of Thessaloniki, General Hospital "Papageorgiou" , Ring Road Efkarpia-Thessaloniki - Greece .
Journal of Clinical and Diagnostic Research : JCDR
|November 12, 2014
Summary
Hepatoblastoma, a common childhood liver tumor, was diagnosed in an infant presenting with an asymptomatic abdominal mass. Surgical removal was successful, confirming a mixed embryonal/fetal subtype.
Area of Science:
- Pediatric Oncology
- Hepatobiliary Surgery
- Developmental Biology
Background:
- Hepatoblastoma is the most frequent primary liver tumor in children.
- It is histologically classified into epithelial, mixed epithelial/mesenchymal, and unspecified types.
- Embryonal tumors are critical to understand for pediatric cancer research.
Observation:
- A 5-month-old girl presented with an asymptomatic abdominal mass.
- Imaging revealed a solid hepatic tumor; lab tests showed thrombocytosis and elevated alpha-fetoprotein.
- The tumor was identified as a mixed embryonal/fetal subtype hepatoblastoma.
Findings:
- Complete surgical excision of the hepatoblastoma was achieved via left lobe hepatectomy.
- Pathological examination confirmed the complete removal of the mixed embryonal/fetal subtype.
- The case highlights successful surgical management of pediatric liver cancer.
Implications:
- Early detection and surgical intervention are crucial for treating pediatric hepatoblastoma.
- Accurate histological subtyping aids in understanding tumor behavior and prognosis.
- This case contributes to the knowledge base for managing embryonal liver tumors in infants.
