Evaluation of BiesseBioscreen as a new methodology for bacteriuria screening

Area of Science:

• Clinical Microbiology
• Medical Diagnostics
• Urinary Tract Infections

Background:

• Urinary tract infections (UTIs) are frequently diagnosed using clinical signs and urine bacterial counts.
• Current microbiology laboratory methods for UTI diagnosis can be time-consuming.

Purpose of the Study:

• To evaluate the BiesseBioscreen analyzer for rapid urine sample analysis.
• To assess the BiesseBioscreen's utility as a preliminary screening tool for UTIs.

Main Methods:

• 962 urine samples from hospital outpatients and inpatients were analyzed.
• Samples were processed using both the BiesseBioscreen analyzer and standard laboratory methods.
• Results from both methods were compared for concordance, sensitivity, and specificity.

Main Results:

• The BiesseBioscreen showed 99.0% sensitivity in ruling out UTIs.
• Concordance with the reference method was 54.9% for negative results and 21.6% for positive results.
• False positive rate was 23.3%, and false negative rate was 0.2%.

Conclusions:

• The BiesseBioscreen analyzer is a suitable system for ruling out urinary tract infections.
• It can effectively screen negative samples, reducing the need for culture tests.
• This method has the potential to decrease diagnosis time, workload, and costs.