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Related Concept Videos

Buffer Systems in the Body01:19

Buffer Systems in the Body

5.7K
Chemical buffers play a critical role in the body's regulation of pH levels. These systems contain one or more compounds that stabilize pH changes by neutralizing strong acids or bases. When pH levels drop, hydrogen ions bind to a weak base; when pH levels rise, hydrogen ions are released. This dynamic process helps maintain pH within a narrow and stable range essential for normal physiological function.
A typical buffer system in bodily fluids includes a weak acid and its corresponding...
5.7K
Buffers02:56

Buffers

178.7K
A solution containing appreciable amounts of a weak conjugate acid-base pair is called a buffer solution, or a buffer. Buffer solutions resist a change in pH when small amounts of a strong acid or a strong base are added. A solution of acetic acid and sodium acetate is an example of a buffer that consists of a weak acid and its salt: CH3COOH (aq) + CH3COONa (aq). An example of a buffer that consists of a weak base and its salt is a solution of ammonia and ammonium chloride: NH3 (aq) + NH4Cl...
178.7K
Buffer Effectiveness02:19

Buffer Effectiveness

58.6K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
58.6K
Buffers: Overview01:30

Buffers: Overview

11.0K
Buffers play a crucial role in stabilizing the pH of a solution by mitigating the effects of small amounts of added acid or base. They consist of a weak acid and its conjugate base or a weak base and its conjugate acid. A solution of acetic acid and sodium acetate is an example of a buffer that consists of a weak acid and its salt: CH3COOH (aq) + CH3COONa (aq). An example of a buffer that consists of a weak base and its salt is a solution of ammonia and ammonium chloride: NH3 (aq) + NH4Cl (aq).
11.0K
Protein Buffers in Blood Plasma and Cells01:20

Protein Buffers in Blood Plasma and Cells

4.8K
The human body utilizes protein buffer systems to maintain a stable pH. These systems capitalize on the dual role of amino acids, which can act as acids or bases by accepting or releasing hydrogen ions in response to pH changes. Protein buffer systems are particularly significant in the extracellular fluid (ECF) and intracellular fluid (ICF) of active cells, where structural and functional proteins provide substantial buffering capacity.
Certain amino acids can exist in a zwitterion state at a...
4.8K
Buffers: Buffer Capacity01:09

Buffers: Buffer Capacity

3.6K
Buffer capacity is the quantitative measure of a buffer to resist the change in pH. As shown in the following equation, the buffer capacity, denoted by 'beta', is expressed as the number of moles of acid or base needed to change the pH of a one-liter buffer solution by 1 unit. Here, Ca and Cb indicate the number of moles of acid and base, respectively. Note that dpH represents the change in pH.
In the graph, pH is plotted as a function of the number of moles of base (Cb) added to a weak...
3.6K

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Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering
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Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

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Kinetic buffers.

Giuseppe Alibrandi1, Luigi Fabbrizzi, Maurizio Licchelli

  • 1Dipartimento di Scienze Chimiche, Università di Messina, Viale F. Stagno d'Alcontres 31, Villaggio S. Agata, 98166 Messina (Italy). galibrandi@unime.it.

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|November 13, 2014
PubMed
Summary
This summary is machine-generated.

A novel molecular device functions as an inverse proton sponge, enabling automatic pH monitoring in reaction vessels. This innovation facilitates real-time analysis of pH-sensitive systems without manual intervention.

Keywords:
kinetic bufferskineticsmacrocycle complexesmolecular devicespH-sensitive systems

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Area of Science:

  • Chemical Engineering
  • Analytical Chemistry
  • Materials Science

Background:

  • Accurate pH monitoring is crucial for understanding and controlling chemical reactions.
  • Existing methods for pH monitoring can be cumbersome or require manual intervention.
  • Development of autonomous systems for chemical analysis is an ongoing research area.

Purpose of the Study:

  • To introduce a new molecular device acting as an inverse proton sponge.
  • To enable automatic and continuous monitoring of pH in reaction vessels.
  • To demonstrate the device's utility in studying pH-sensitive systems and chemical reactions.

Main Methods:

  • The device is a composite of an alkyl chloride (acid generator) and a buffer (pH modulator).
  • Computer simulations were used to generate pH versus time profiles under various conditions.
  • Automatic spectrophotometric titrations were performed without an autoburette to test the device.

Main Results:

  • The molecular device successfully created a slow decrease in pH within the reaction vessel.
  • Computer simulations accurately predicted pH-time profiles.
  • The device enabled automatic spectrophotometric titrations, demonstrating its practical application.

Conclusions:

  • The proposed molecular device offers a novel approach for inverse proton sponge functionality.
  • This system allows for the automatic monitoring of pH-sensitive systems.
  • The device has potential applications in various chemical analyses, including monitoring acid uptake by metal complexes.