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Published on: September 20, 2018
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Chorioretinal nocardiosis
Christina E Horvath1, Christian K Brinkmann, Christoph Ozdoba
1From *Klinik und Poliklinik für Augenheilkunde, Inselspital, University Bern; and †Institut für Diagnostische und Interventionelle Neuroradiologie and ‡Institut für Infektionskrankheiten, Universität Bern, Switzerland.
Retinal Cases & Brief Reports
|November 13, 2014
Summary
Disseminated nocardiosis can affect the eye, causing choroidal lesions in immunosuppressed individuals. Prompt sulfonamide treatment led to favorable visual recovery in this case report.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Medical Microbiology
Background:
- Disseminated nocardiosis is a rare systemic infection, often occurring in immunocompromised patients.
- Ocular involvement in nocardiosis can present with diverse clinical manifestations, including choroidal lesions.
- Early diagnosis and treatment are crucial for managing nocardial infections.
Purpose of the Study:
- To describe the ocular manifestations of disseminated nocardiosis.
- To report a case of endogenous nocardiosis with a choroidal lesion.
- To highlight the importance of timely intervention for ocular nocardiosis.
Main Methods:
- A case report of an immunosuppressed patient with disseminated nocardiosis.
- Clinical presentation of a unilateral extramacular choroidal lesion.
- Treatment with sulfonamides for culture-proven nocardia infection.
- Ophthalmological examination and visual acuity monitoring during follow-up.
Main Results:
- The patient presented with a choroidal lesion in one eye.
- Following treatment, the lesion showed demarcation and resolution.
- Secondary macular pucker with vitreoretinal traction and macular edema developed.
- Visual acuity improved from 20/100 to 20/32 in the affected eye.
Conclusions:
- Ocular endogenous nocardiosis can be successfully treated.
- Early and appropriate treatment of nocardial choroiditis leads to favorable visual outcomes.
- Immunosuppressed patients with systemic nocardiosis require careful ophthalmological surveillance.
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