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Intraocular metastasis of testicular natural killer T-cell lymphoma with diffuse retinal pigment epithelium changes
1From the Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut.
Purpose:
The purpose of this study was to report the first confirmed case of testicular natural killer T-cell lymphoma with bilateral intraocular metastasis.
Methods:
The author presents a chart review of a patient with testicular natural killer T-cell lymphoma metastasis to both eyes. This patient was treated with systemic chemotherapy, radiation, and intravitreal injections of methotrexate.
Results:
The author identified one case of a patient with the diagnosis of bilateral metastatic natural killer T-cell lymphoma with ocular involvement treated with intravitreal methotrexate. After treatment, the patient developed diffuse widespread retinal pigment epithelium alterations in giraffe-like patterns.
Conclusion:
This represents a clinical case of a patient with primary testicular natural killer T-cell lymphoma and ocular metastasis with posttreatment retinal changes resembling bilateral diffuse uveal melanocytic proliferation.
