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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
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Dengue Fever presenting with macular hemorrhages
Pawan Gupta1, Chikirsha Jain, Ankur Aggarwal
1From the Vitreo Retina and Uveitis, Venu Eye Institute and Research Centre, New Delhi, India.
Retinal Cases & Brief Reports
|November 13, 2014
Summary
Undiagnosed dengue fever can cause vision loss due to ocular issues like retinal hemorrhages. Early diagnosis and treatment, potentially with steroids, may improve visual outcomes in affected patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Medical Diagnostics
Background:
- Dengue fever is a mosquito-borne viral illness with diverse clinical presentations.
- Ocular manifestations of dengue fever are not always recognized, especially in mild or undiagnosed cases.
Purpose of the Study:
- To document and analyze the ocular findings in patients presenting with previously undiagnosed dengue fever.
- To highlight the importance of considering dengue fever in the differential diagnosis of sudden vision loss.
Main Methods:
- Retrospective case series of three patients with sudden, painless vision loss and a history of fever.
- Ophthalmologic examinations included fundus photography, fluorescein angiography, and optical coherence tomography.
- Systemic evaluation and dengue serology were performed to confirm the diagnosis.
Main Results:
- All three patients were diagnosed with dengue fever retrospectively.
- Common ocular findings included retinal hemorrhages (100%) and subhyaloid hemorrhages (66%).
- One patient presented with retinitis-like lesions, showing visual improvement with oral steroid treatment.
Conclusions:
- A notable proportion of mild dengue fever cases may remain undiagnosed.
- Ocular manifestations, including retinal hemorrhages, can be significant indicators of dengue fever.
- Prompt ophthalmologic evaluation is crucial for patients with suspected dengue and visual disturbances.
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