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Updated: Apr 21, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
Spontaneous resolution of total retinal detachment in coats disease
Anthony B Daniels1, Scott E Brodie, David H Abramson
1From the Departments of *Surgery and †Medicine, Memorial Sloan-Kettering Cancer Center; ‡Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York.
Purpose:
To present a case of a child with total retinal detachment secondary to Coats disease who failed different treatment modalities and then had spontaneous resolution of the retinal detachment years later.
Methods:
Case report.
Results:
After progressing to total retinal detachment despite multimodality therapy with intravitreal bevacizumab and laser photocoagulation for advanced Coats disease, the patient was watched routinely for almost 2 years. On routine follow-up, he was noted to have complete resolution of the total retinal detachment with a completely flat retina.
Conclusion:
Resolution of advanced Coats disease with total retinal detachment rarely occurs.

