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Updated: Apr 21, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Unusual case of diffuse choroidal melanoma masquerading as atypical central serous chorioretinopathy
Adrienne W Scott1, Sharon Fekrat, Prithvi Mruthyunjaya
1From the *Department of Ophthalmology, Albert Eye Research Institute, Duke University Eye Center, and †Department of Pathology, Duke University Medical Center, Durham, North Carolina; and ‡Vitreous-Retina-Macula Consultants of New York, New York Eye and Ear Infirmary, New York.
Purpose:
To describe an unusual case of diffuse circumpapillary choroidal melanoma masquerading as atypical central serous chorioretinopathy, and to describe fluorescein angiographic and optical coherence tomography characteristics of this diffuse choroidal melanoma.
Design:
Interventional case report.
Methods:
A 46-year-old human immunodeficiency virus-positive man presented with an 11-month history of decreased vision and the absence of an elevated choroidal lesion. The patient failed to return for follow-up.
Results:
Thirteen months after his initial presentation, circumpapillary diffuse choroidal melanoma was diagnosed. The patient underwent enucleation. No extrascleral extension was present.
Conclusions:
Imaging characteristics on fluorescein angiography or optical coherence tomography may be of diagnostic value to aid the ophthalmologist in earlier detection of diffuse choroidal melanomas.
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