Related Experiment Video
Updated: Apr 21, 2026

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
Published on: May 31, 2024
Repeated noninfectious endophthalmitis after intravitreal administration of bevacizumab: a report of two cases
Shiri Soudry1, Anat Loewenstein, Joseph Moisseiev
1From the *Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv; †Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv; and ‡Department of Ophthalmology, Sheba Medical Center, Tel Hashomer, Israel.
Purpose:
To report on two patients with sterile endophthalmitis recurring twice after intravitreal bevacizumab injection.
Methods:
Two cases of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab are described, followed by a review of the literature.
Results:
Two patients presented with painful eyes and decreased vision associated with endophthalmitis several days after intravitreal bevacizumab injection. In both patients, vitreous specimens were sterile. The intraocular inflammation recurred after additional intravitreal injection of bevacizumab that was performed during subsequent follow-up.
Conclusion:
This is the first report of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab. Awareness of the possible association between bevacizumab administration and sterile endophthalmitis may be warranted.
Related Concept Videos
Glaucoma: Overview
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

