Autofluorescence of choroidal melanomas
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Updated: Apr 21, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Karim Bakri1, Jose S Pulido, Sophie J Bakri
1From the Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Purpose:
To report autofluorescence findings for two patients with choroidal melanomas.
Methods:
Records and photographs for two patients with choroidal melanomas were reviewed. Fundus autofluorescence photography was performed using the Heidelberg confocal SLO system (Heidelberg Retina Angiograph; Heidelberg Engineering, Dossenheim, Germany).
Results:
Both patients had lipofuscin over the melanoma. In Case 1, autofluorescence studies showed a linear streak of autofluorescence and patchy autofluorescence overlying the tumor. In Case 2, autofluorescence photographs showed the presence of small flecklike areas of autofluorescence over the melanoma.
Conclusion:
Fundus autofluorescence photography is an alternative method for imaging lipofuscin over choroidal lesions.
