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Spectral domain optical coherence tomography findings in tamoxifen retinopathy--a case report
Sandhya Narayanan Nair1, Giridhar Anantharaman, Mahesh Gopalakrishnan
1From the Giridhar Eye Institute, Kadavanthra, India.
Purpose:
To report spectral domain optical coherence tomography findings in a case of typical tamoxifen retinopathy.
Methods:
In this observational case report, a patient with tamoxifen retinopathy was imaged with spectral domain optical coherence tomography and fundus auto fluorescence.
Results:
Spectral domain optical coherence tomography showed numerous hyperreflective spots within the retina, mainly in the inner retinal layers in both the eyes. The external limiting membrane, the Inner Segment-Outer Segment junction, and the photoreceptors were not discernable at the fovea in the right eye. In the left eye, there was foveal atrophy with total loss of photoreceptors. The autofluorescent images showed macular hypofluorescence with foveal hyperfluorescence.
Conclusion:
Spectral domain optical coherence tomography demonstrated abnormalities in the outer retinal layers in tamoxifen retinopathy. There were also characteristic alterations in the autofluorescence pattern at the macula in tamoxifen retinopathy.
