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Paracentral cone dystrophy with tapetal-like sheen and mizuo phenomenon examined with different imaging techniques
Guillermo Salcedo-Villanueva1, Juan M Jimenez-Sierra
1Retina Department, Asociacion Para Evitar la Ceguera en Mexico, Mexico City, Mexico.
Purpose:
To present a case report of a patient diagnosed with cone dystrophy, with an uncommon presentation of paracentral involvement, tapetallike sheen, and Mizuo phenomenon.
Methods:
The patient underwent complete ophthalmic examination, repeated electroretinograms, fluorescein angiography, spectral-domain optical coherence tomography, autofluorescence, and different techniques for fundus photographs (color, infrared, red free).
Patient:
Twenty-year-old male patient who manifested slight photofobia but was otherwise asymptomatic.
Results:
The patient had 20/20 vision in both eyes. Upon indirect ophthalmoscopy, the retina presented a metalliclike sheen. Sequential electroretinograms and multifocal electroretinogram demonstrated a decreasing photopic response, with paracentral involvement. Autofluorescence and spectral-domain optical coherence tomography allowed a better visualization of the atrophic parafoveal cones. Red-free photographs help document the tapetallike sheen and Mizuo phenomenon after 3-hour dark adaptation.
Conclusion:
The final diagnosis of cone dystrophy, paracentral, with tapetallike sheen was established. Spectral-domain optical coherence tomography and red-free photographs will help better understand the pathophysiology and clinical manifestations of this uncommon disease.

