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Updated: Apr 21, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Adverse reactions to plain gut, polyglycolic Acid, and polyglactin 910 sutures for sclerotomy closure at pars plana
Jason A Croskrey1, Dennis P Han
1Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Purpose:
To evaluate the rates of adverse reactions to suture materials and compare the rates for plain gut, polyglycolic acid, and polyglactin 910.
Methods:
Postoperative adverse suture reaction rates were compared using Fisher exact test. One hundred and forty-six patients who underwent pars plana vitrectomy were included in this study.
Results:
Adverse suture reaction rates were 2% (1/48) for plain gut, 30% (6/20) for polyglycolic acid, and 12% (11/78) for polyglactin 910.
Conclusion:
Plain gut suture was associated with fewer adverse suture reactions when compared with polyglycolic acid and polyglactin 910 and seems to be suitable for sclerotomy closure.

