The UCSC Cancer Genomics Browser: update 2015.

Area of Science:

• Genomics
• Bioinformatics
• Cancer Research

Background:

• The increasing volume of cancer genomic data requires integrated platforms for analysis and visualization.
• Effective tools are needed to explore relationships between genomic alterations and clinical phenotypes.

Purpose of the Study:

• To introduce the UCSC Cancer Genomics Browser as a comprehensive web-based application.
• To facilitate the discovery and sharing of research observations in cancer genomics.

Main Methods:

• Integration of diverse -omic data with clinical and phenotypic features.
• Visualization of genomic alterations alongside patient characteristics (age, subtype, biomarkers).
• Hosting of 575 public datasets from major cancer genomics initiatives.

Main Results:

• The platform allows dynamic generation of Kaplan-Meier plots and data export to Galaxy.
• Users can upload/download clinical data and create shareable URL bookmarks.
• Facilitates exploration of over 227,000 cancer samples.

Conclusions:

• The UCSC Cancer Genomics Browser provides a powerful, user-friendly resource for cancer researchers.
• It enhances the ability to investigate genotype-phenotype correlations and share findings effectively.