Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fetal Circulation

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

Acute Respiratory Failure-II

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

Breathing

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Socioeconomic burden of multiple sclerosis: Insights from a cohort in Coimbra, Portugal.

Multiple sclerosis and related disorders·2026

Same author

Aliança AMARTE: A Collaborative Network to Improve Oncologic Pediatric Care in Brazil.

Pediatric blood & cancer·2025

Same author

Predicting diagnostic conversion from mild cognitive impairment to Alzheimer's disease: A Bayesian hierarchical model approach using ADNI patient data.

Journal of Alzheimer's disease : JAD·2025

Same author

Modeling the COVID-19 vaccination process using the FRAM Method.

Ciencia & saude coletiva·2025

Same author

Epidemic Surveillance of Covid-19: Considering Uncertainty and Under-Ascertainment.

Portuguese journal of public health·2025

Same author

Effectiveness of anti-CD20 therapies following natalizumab discontinuation: insights from a cohort study.

Multiple sclerosis and related disorders·2025

Search research articles

Related Experiment Video

Updated: Apr 21, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Fetal bronchopulmonary malformations.

Carla Nunes¹, Isabel Pereira¹, Cláudia Araújo¹

¹a Departamento/Clínica Universitária de Obstetrícia e Ginecologia , CHLN - Hospital Universitário de Santa Maria , Lisboa , Portugal.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

|November 15, 2014

Summary

This summary is machine-generated.

Fetal lung masses, including congenital cystic adenomatoid malformation and bronchopulmonary sequestration, often stabilize or regress in utero. With appropriate postnatal care and surgery, children experience normal development and a good prognosis.

Keywords:

Bronchopulmonary sequestration cystic adenomatoid malformation prenatal diagnosis

More Related Videos

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

Published on: October 19, 2013

Related Experiment Videos

Last Updated: Apr 21, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

Published on: October 19, 2013

Area of Science:

Perinatology
Pediatric Surgery
Developmental Biology

Background:

Fetal body tumors are rare, with chest masses often stemming from bronchopulmonary malformations.
Congenital cystic adenomatoid malformation (CCAM) and bronchopulmonary sequestration (BPS) account for a significant portion of prenatal lung lesions.

Purpose of the Study:

To analyze the diagnosis, evolution, management, and outcomes of fetal bronchopulmonary malformations.
To assess the prognosis of infants diagnosed with these congenital lung anomalies.

Main Methods:

Retrospective analysis of CCAM and BPS cases diagnosed between 2003 and 2013.
Review of prenatal imaging, clinical management, and long-term patient outcomes.

Main Results:

17 cases of fetal bronchopulmonary malformations were identified among 918 fetal malformations.
Most lesions were diagnosed in the second trimester and showed intrauterine regression or stabilization.
Nine infants required surgery, and all children achieved healthy development with regular pediatric surveillance.

Conclusions:

Fetal lung masses are frequently isolated findings with a tendency for intrauterine regression.
Adequate postnatal surveillance and timely surgical intervention lead to a favorable prognosis for affected children.