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Updated: Apr 21, 2026

Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue
Published on: June 21, 2018
[Starvation is a rare cause of metabolic ketoacidosis]
Thea Vestergaard1, Jeppe Frøkjær Aaen, Jens Meldgaard Bruun
1Sjællandsgade 65, 1., 8000 Aarhus C. theakalender@gmail.com.
Abstract:
A 79-year-old woman with no medical history was admitted under the diagnosis of stroke. Two months prior she had a fractured tibia, complicated by osteomyelitis. Physical examination showed dehydration and malnourishment. Chest X-ray revealed pneumonia and laboratory data revealed signs of infection, dehydration and normoglycaemic metabolic acidosis with elevated P-3-hydroxybutyrate. The case presents a starvation- (weight loss ~ 13 kg) and infection-induced non-diabetic metabolic ketoacidosis treated with intravenous supplementation of isotonic saline, potassium, bicarbonate and insulin.
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