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Updated: Apr 21, 2026

A Murine Model of Carotid Aneurysm Formation
Published on: September 9, 2025
[Cardiac myxomas may cause cerebral aneurysms]
Frederik Winsløw1, Per Meden, Marie Elisabeth Cortsen
1Neurologisk Afdeling N, Bispebjerg Hospital, -Bispebjerg bakke 23, 2400 København NV. pmed0001@bbh.regionh.dk.
Insights
Cardiac myxoma resection can rarely lead to cerebral aneurysms. This case highlights a patient who developed multiple brain aneurysms and intracranial hemorrhage a year after myxoma removal.
Area of Science:
- Neurology
- Cardiology
- Vascular Surgery
Background:
- Cardiac myxomas are primary heart tumors, rarely associated with systemic embolization.
- Neurological complications from cardiac myxomas are uncommon, typically presenting as stroke or transient ischemic attacks.
Observation:
- A 50-year-old male presented with symptoms of intracranial hemorrhage.
- Imaging revealed multiple bilateral middle cerebral artery aneurysms.
- The patient had undergone resection of a cardiac myxoma one year prior.
Findings:
- The patient developed cerebral aneurysms post-cardiac myxoma resection.
- Digital subtraction angiography confirmed multiple fusiform intracranial aneurysms.
- The presentation suggests a potential link between cardiac myxoma and aneurysm formation.
Implications:
- This case underscores the importance of considering neurological complications after cardiac myxoma surgery.
- Further research into the molecular mechanisms linking cardiac myxomas to aneurysm development is warranted.
- Enhanced surveillance for vascular abnormalities may be beneficial in patients with a history of cardiac myxoma.
Abstract:
Cerebral aneurysm following a cardiac myxoma is a rare neurological complication. We report a 50-year-old man who developed cerebral aneurysms one year after resection of a cardiac myxoma. Magnetic resonance imaging of the brain showed features of intracranial haemorrhage. Digital subtraction angiography showed several fusiform intracranial aneurysms bilaterally in the middle cerebral artery. Finally, we discuss potential molecular mechanisms of the development of myxomatous aneurysms.
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