Risk Factors Associated With Abscess Formation in Children 5 Years of Age and Younger

Vaidehi Agrawal1, Avery Wright2, Brinda Mehta2

  • 1Department of Surgery, Driscoll Children's Hospital, Corpus Christi, TX, USA.

Clinical Pediatrics
|November 15, 2014
PubMed

Insights

Hospitalizations for pediatric soft tissue abscesses have doubled. Key risk factors include family history and younger age (2 years and under) in children, with Staphylococcus aureus being a common cause.

Area of Science:

  • Pediatric Medicine
  • Infectious Diseases
  • Dermatology

Background:

  • Hospitalization rates for pediatric soft tissue abscesses requiring incision and drainage have doubled between 1997 and 2009.
  • There is a growing need to identify risk factors for pediatric abscess formation due to the increasing national burden.

Purpose of the Study:

  • To evaluate physiological and lifestyle parameters as potential risk factors for soft tissue abscess formation in pediatric patients aged 5 years or younger.
  • To identify key demographic and etiological factors associated with increased risk.

Main Methods:

  • Retrospective analysis of pediatric patient data.
  • Evaluation of demographic factors (age), family history, and microbiological data (pathogen identification).

Main Results:

  • Family history and younger age (≤2 years) were identified as significant risk factors for abscess formation.
  • Methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA) were the predominant pathogens identified.

Conclusions:

  • Pediatricians can utilize identified risk factors, such as family history and young age, to counsel high-risk families on prevention strategies.
  • Early identification and intervention for high-risk groups may help reduce healthcare costs associated with incision and drainage procedures.

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
5
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.7K
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
78
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
118
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
48
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
895