Genome editing using Cas9 nickases

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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

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Alexandro E Trevino1, Feng Zhang1

  • 1Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Methods in Enzymology
|November 16, 2014
PubMed

Keywords:
CRISPRCas9Gene targetingGenome editingNucleases

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