Surgery for Recurrent Biliary Tract Cancer: A Single-center Experience With 74 Consecutive Resections
Yu Takahashi1, Tomoki Ebata, Yukihiro Yokoyama
1*Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan; and †Department of Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Annals of Surgery
|November 19, 2014
Summary
Surgery for recurrent biliary tract cancer (BTC) can improve survival in selected patients. This review found that surgical resection offers a better chance of long-term survival for patients with recurrent BTC.
Area of Science:
- Oncology
- Surgical Oncology
- Gastrointestinal Surgery
Background:
- Recurrent biliary tract cancer (BTC) presents a challenge due to limited data on surgical intervention effectiveness.
- The survival benefit of surgery for recurrent BTC remains unclear, necessitating further investigation.
Purpose of the Study:
- To evaluate the outcomes and survival benefits of surgical resection for patients with recurrent biliary tract cancer (BTC).
Main Methods:
- Retrospective review of 606 patients with recurrent BTC (gallbladder cancer and cholangiocarcinoma) between 1991 and 2010.
- Comparison of outcomes between 74 patients who underwent resection for recurrence and 532 patients who did not.
Main Results:
- Patients undergoing surgery for recurrence had less advanced disease and longer time to recurrence (1.4 vs 0.8 years).
- Survival after recurrence was significantly better in the surgical group (32% at 3 years) compared to the non-surgical group (3% at 3 years).
- Independent prognostic factors for survival after surgery included primary tumor nodal status and recurrence site.
Conclusions:
- Surgical resection for recurrent BTC is a safe procedure for selected patients.
- Surgery for recurrent BTC can lead to improved long-term survival outcomes.
