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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.8K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-I: Introduction01:29

Asthma-I: Introduction

3.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.8K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

5.0K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
5.0K
Asthma I: Introduction01:28

Asthma I: Introduction

16
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
16
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.4K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.4K
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

20
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
20

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Related Experiment Video

Updated: Apr 20, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
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Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

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Obesity and asthma: current knowledge and future needs.

Pradeesh Sivapalan1, Zuzana Diamant, Charlotte Suppli Ulrik

  • 1aDepartment of Pulmonary Medicine, Hvidovre Hospital, Hvidovre, Denmark bDepartment of Respiratory Medicine and Allergology, Skåne University Hospital, Sweden cDepartment of General Practice & QPS-NL, Groningen, the Netherlands dUniversity of Copenhagen, Copenhagen, Denmark.

Current Opinion in Pulmonary Medicine
|November 19, 2014
PubMed
Summary
This summary is machine-generated.

Obesity is linked to a distinct asthma phenotype that is harder to manage and less responsive to medication. Weight reduction can significantly improve asthma symptoms and outcomes in obese individuals.

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Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
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Area of Science:

  • Pulmonology
  • Metabolic Disorders
  • Clinical Medicine

Background:

  • Obesity significantly impacts asthma incidence and clinical presentation.
  • The interplay between obesity and asthma is complex, affecting disease management.
  • Obesity is associated with increased asthma prevalence and severity.

Purpose of the Study:

  • To review recent findings on the association between obesity and asthma.
  • To explore underlying mechanisms, clinical features, and treatment responses.
  • To evaluate the effect of weight reduction on asthma control.

Main Methods:

  • Review of clinical and epidemiological studies.
  • Analysis of data on asthma phenotypes in obese individuals.
  • Synthesis of research on comorbidities and treatment efficacy.

Main Results:

  • Obese asthma patients exhibit a unique phenotype: difficult-to-control, less responsive to medications, and higher healthcare use.
  • Common comorbidities link obesity and asthma, contributing to the obese-asthma phenotype.
  • Even modest weight reduction improves asthma manifestations and outcomes.

Conclusions:

  • Obese and overweight asthma patients have poorer control and reduced response to corticosteroids compared to normal-weight individuals.
  • Further research is needed to understand the mechanisms linking obesity and asthma.
  • Targeted management strategies for the obese-asthma phenotype are required.