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Updated: Apr 20, 2026
An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
Published on: August 30, 2017
Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared
Sheng Wang1, Lei Zhang, Chunhong Dong
1Institute of Nanobiotechnology, School of Life Sciences, School of Materials Science and Engineering, Tianjin University and Tianjin Key Laboratory of Composites and Functional Materials, Tianjin, 300072, PR China. jinchang@tju.edu.cn wanghj@tju.edu.cn.
Abstract:
A smart pH-responsive photodynamic therapy system based on upconversion nanoparticle loaded PEG coated polymeric lipid vesicles (RB-UPPLVs) was designed and prepared. These RB-UPPLVs which are promising agents for deep cancer photodynamic therapy applications can achieve enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.
