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Updated: Apr 20, 2026
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Published on: October 15, 2013
An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of
R Burger1, D Kurzbuch, R Gorkin
1Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Physical Sciences, Dublin City University, Ireland. jens.ducree@dcu.ie.
Abstract:
In this work we present a centrifugal microfluidic system enabling highly efficient collective trapping and alignment of particles such as microbeads and cells, their multi-colour fluorescent detection and subsequent manipulation by optical tweezers. We demonstrate array-based capture and imaging followed by "cherry-picking" of individual particles, first for fluorescently labelled polystyrene (PS) beads and then for cells. Different cell lines are discriminated based on intracellular as well as surface-based markers.
