Transcatheter aortic valve replacement: current perspectives and future implications

Area of Science:

• Cardiology
• Interventional Cardiology
• Medical Technology

Background:

• Severe symptomatic aortic stenosis (AS) poses significant risks, particularly for elderly patients with comorbidities.
• Transcatheter aortic valve replacement (TAVR) has emerged as a key therapeutic option for inoperable or high-risk patients.
• Existing evidence from registries and trials supports TAVR's safety and efficacy in improving survival and function.

Purpose of the Study:

• To review current perspectives on patient selection for TAVR.
• To discuss risk assessment strategies pertinent to TAVR candidates.
• To outline procedural considerations and outcomes associated with TAVR.

Main Methods:

• Review of multicentre registries and randomized trials on TAVR.
• Analysis of patient selection criteria and risk stratification models.
• Examination of procedural techniques and post-procedure management.

Main Results:

• TAVR demonstrates significant benefits in survival and functional capacity for selected AS patients.
• Comorbidities in elderly patients can impact TAVR outcomes, necessitating precise risk assessment.
• Multidisciplinary heart valve teams are essential for comprehensive TAVR care.

Conclusions:

• Optimal patient selection and risk assessment are paramount for successful TAVR.
• A multidisciplinary approach is vital throughout the TAVR process, from evaluation to post-procedure care.
• TAVR represents a significant advancement in managing severe aortic stenosis.