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Updated: Apr 20, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Current and future oral systemic therapies for psoriasis.
John B Kelly1, Peter Foley2, Bruce E Strober3
1Department of Dermatology, University of Connecticut Health Center, Farmington, CT, USA.
Dermatologic Clinics
|November 22, 2014
Summary
Systemic oral medications offer varied efficacy and safety for moderate to severe psoriasis. Appropriate monitoring allows for monotherapy or combination use, with promising new drugs in development.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Psoriasis is a chronic inflammatory skin condition affecting a significant patient population.
- Current treatment landscape includes oral and systemic medications with variable outcomes.
Purpose of the Study:
- To review the current oral, systemic medications for moderate to severe psoriasis.
- To discuss the safety, efficacy, and monitoring requirements of these therapies.
- To highlight the potential of emerging pharmaceutical agents.
Main Methods:
- Literature review of existing psoriasis treatments.
- Analysis of clinical data on oral and systemic psoriasis therapies.
- Overview of ongoing research and drug development pipelines.
Main Results:
- A wide array of oral, systemic psoriasis treatments are available.
- Efficacy and safety profiles differ among available medications.
- Combination therapy and monotherapy are viable treatment strategies with proper patient monitoring.
Conclusions:
- Systemic oral therapies are crucial for managing moderate to severe psoriasis.
- Careful patient monitoring is essential for optimizing treatment benefits and mitigating risks.
- Future research promises novel therapeutic options for psoriasis patients.
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