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Synovial sarcoma: MR imaging.

H Mahajan1, J G Lorigan, A Shirkhoda

  • 1Department of Diagnostic Radiology, University of Texas, M.D. Anderson Cancer Center, Houston.

Magnetic Resonance Imaging
|March 1, 1989
PubMed
Summary
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Magnetic resonance (MR) imaging helps evaluate synovial sarcoma extent and treatment response. While MR lacks specific signal intensity for synovial sarcoma, it effectively assesses tumor size and changes after chemotherapy, indicating treatment efficacy.

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Synovial sarcoma is a rare soft tissue sarcoma.
  • Accurate staging and treatment response assessment are crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the utility of magnetic resonance (MR) imaging in assessing synovial sarcoma.
  • To determine MR imaging's role in defining tumor extent and response to chemotherapy.

Main Methods:

  • Ten patients with biopsy-proven synovial sarcoma underwent MR imaging on a 1.5-T unit.
  • Serial MR examinations were performed on four patients post-chemotherapy.

Main Results:

  • Synovial sarcomas exhibited intermediate T1-weighted and heterogeneous high T2-weighted signal intensities.

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  • MR imaging identified tumor demarcation, adjacent bone involvement, vascular invasion, and hemorrhage.
  • Post-chemotherapy MR showed decreased tumor size and increased T2 signal intensity in three patients, correlating with clinical response and indicating necrosis.

    • Conclusions:

    • MR imaging is valuable for defining the extent of synovial sarcoma.
    • MR imaging effectively assesses treatment response in synovial sarcoma, correlating with clinical outcomes.
    • While not specific, MR imaging findings aid in managing synovial sarcoma patients.