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Updated: Apr 20, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
The Victor C++ library for protein representation and advanced manipulation
Layla Hirsh1, Damiano Piovesan2, Manuel Giollo1
1Department of Biomedical Sciences, University of Padua, Viale G. Colombo 3, 35131 Padova, Italy, Department of Engineering, Pontificia Universidad Católica del Perú, San Miguel, 32 Lima, Perú and Department of Information Engineering, University of Padua, Via Gradenigo 6, 35121 Padova, Italy Department of Biomedical Sciences, University of Padua, Viale G. Colombo 3, 35131 Padova, Italy, Department of Engineering, Pontificia Universidad Católica del Perú, San Miguel, 32 Lima, Perú and Department of Information Engineering, University of Padua, Via Gradenigo 6, 35121 Padova, Italy.
The VIrtual Constrution TOol for pRoteins (Victor) is an open-source C++ library simplifying complex protein analysis. It supports various applications and offers extensive documentation for users of all levels.
Area of Science:
- Computational Biology
- Bioinformatics
- Structural Biology
Background:
- Protein sequence and structure analysis necessitates specialized software libraries for complex methods.
- The VIrtual Constrution TOol for pRoteins (Victor) C++ library is introduced as an open-source platform.
- Victor aims to empower users with limited experience to develop advanced protein analysis tools.
Purpose of the Study:
- To present the Victor C++ library for protein sequence and structure manipulation.
- To facilitate the development of advanced computational tools for protein analysis.
- To foster community contributions and provide a robust platform for research.
Main Methods:
- Development of a C++ library named Victor.
- Implementation of features for statistical energy potentials, profile-profile sequence alignments, and ab initio loop modeling.
- Provision of source files, unit tests, and comprehensive online documentation (Wiki, tutorials, examples, Doxygen).
Main Results:
- Victor has been utilized in numerous publications over 15 years, demonstrating its reliability and efficiency.
- The library supports a range of advanced applications in protein analysis.
- Extensive documentation and community support are available.
Conclusions:
- Victor is a valuable and efficient open-source C++ library for protein sequence and structure analysis.
- Its design caters to both inexperienced and experienced users, promoting accessibility and collaboration.
- The library's long-standing use and comprehensive resources make it a significant tool in bioinformatics.
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