Related Experiment Video
Updated: Apr 20, 2026

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
Published on: June 20, 2020
Pediatric health-related quality of life: a structural equation modeling approach
Ester Villalonga-Olives1, Ichiro Kawachi2, Josué Almansa3
1Institute of Medical Psychology and Medical Sociology, Georg-August-University Göttingen, Göttingen, Germany; Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts, United States of America.
Insights
The Wilson and Cleary framework for measuring Health Related Quality of Life (HRQoL) was tested in German children. Results showed differences from adult models, highlighting a need for pediatric-specific HRQoL theory and evaluation.
Area of Science:
- Pediatric Health Outcomes Research
- Quality of Life Measurement
Background:
- The Wilson and Cleary framework is a key model for assessing Health Related Quality of Life (HRQoL).
- While validated in adults, this framework has not been empirically tested in pediatric populations.
- A lack of standardized measures and definitions for pediatric HRQoL exists.
Purpose of the Study:
- To empirically investigate the applicability of the Wilson and Cleary framework in a pediatric population.
- To assess the measurement structure of the framework in young children.
Main Methods:
- Structural equation modeling was employed.
- Data were collected from 214 German children aged 3-5 years.
- Factors assessed included symptom status, functional status (developmental), social-emotional behavior, and social environment (socioeconomic status, area of education).
Main Results:
- The model demonstrated good fit (χ2 = 5.5, df = 6, p = 0.48, SRMR = 0.01).
- Area of education and developmental status significantly influenced HRQoL, explaining 15% of its variance.
- Symptom status did not significantly impact the model. Developmental status was influenced by area of education, socioeconomic status, and individual behavior.
Conclusions:
- The Wilson and Cleary framework shows potential for use in children, but significant differences exist compared to adult applications.
- These discrepancies indicate a conceptual gap in understanding pediatric HRQoL.
- Further development of pediatric-specific HRQoL theory and evaluation methods is recommended.
Objectives:
One of the most referenced theoretical frameworks to measure Health Related Quality of Life (HRQoL) is the Wilson and Cleary framework. With some adaptions this framework has been validated in the adult population, but has not been tested in pediatric populations. Our goal was to empirically investigate it in children.
Methods:
The contributory factors to Health Related Quality of Life that we included were symptom status (presence of chronic disease or hospitalizations), functional status (developmental status), developmental aspects of the individual (social-emotional) behavior, and characteristics of the social environment (socioeconomic status and area of education). Structural equation modeling was used to assess the measurement structure of the model in 214 German children (3-5 years old) participating in a follow-up study that investigates pediatric health outcomes.
Results:
Model fit was χ2 = 5.5; df = 6; p = 0.48; SRMR = 0.01. The variance explained of Health Related Quality of Life was 15%. Health Related Quality of Life was affected by the area education (i.e. where kindergartens were located) and development status. Developmental status was affected by the area of education, socioeconomic status and individual behavior. Symptoms did not affect the model.
Conclusions:
The goodness of fit and the overall variance explained were good. However, the results between children' and adults' tests differed and denote a conceptual gap between adult and children measures. Indeed, there is a lot of variety in pediatric Health Related Quality of Life measures, which represents a lack of a common definition of pediatric Health Related Quality of Life. We recommend that researchers invest time in the development of pediatric Health Related Quality of Life theory and theory based evaluations.
Related Concept Videos
Modeling in Therapy
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Pharmacokinetics in Pediatric Patients: Drug Metabolism
