Related Experiment Video
Updated: Apr 20, 2026
07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
2.1K
Odontomas and supernumerary teeth: is there a common origin?
1"Sapienza" University of Rome - Department of Odontostomatological and Maxillo Facial Sciences - Via Caserta 6, 00161 Rome - Italy.
International Journal of Medical Sciences
|November 25, 2014
Summary
Similarities in location and pathology suggest odontomas and supernumerary teeth may stem from a single malformative or hamartomatous process, despite distinct classifications. Further research into common genetic factors is indicated.
Area of Science:
- Dentistry
- Oral Pathology
- Genetics
Background:
- Odontomas and supernumerary teeth are distinct dental anomalies.
- Their etiologies are not fully understood.
- Potential shared underlying mechanisms warrant investigation.
Purpose of the Study:
- To analyze scientific evidence for similarities between odontomas and supernumerary teeth.
- To explore the possibility of a unified explanation for these dental anomalies.
- To investigate common etiologic factors.
Main Methods:
- Conducted a literature search for epidemiologic studies.
- Indexed studies in PubMed to determine worldwide incidence.
- Analyzed existing literature data for similarities.
Main Results:
- Identified similarities in topographic distribution between odontomas and supernumerary teeth.
- Observed comparable pathologic manifestations.
- Found indications of common genetic and immuno-histochemical factors.
Conclusions:
- Despite separate classifications, odontomas and supernumerary teeth may represent manifestations of the same underlying pathologic process.
- This process could be either malformative or hamartomatous.
- Evidence suggests shared genetic and immuno-histochemical pathways.
Related Concept Videos
01:15Teeth
2.4K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.4K
01:21Tooth Anatomy
3.1K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
3.1K
01:28Development of the Oral Microbiota
48
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
48
01:29Bone Formation by Intramembranous Ossification
17.8K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
17.8K
01:27The Oral Microbiota
63
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
63
01:24Bone Formation by Endochondral Ossification
16.1K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
16.1K