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Absorption of Tc-99m pertechnetate from the augmented bladder during direct nuclear cystography
B Lowe1, W F Barnes, J C Leonard
1Nuclear Medicine Service, Children's Hospital of Oklahoma, Oklahoma City 73126.
Clinical Nuclear Medicine
|May 1, 1989
Summary
Tc-99m sulfur colloid is recommended for augmented bladder imaging. It helps prevent misdiagnosis of vesicoureteral reflux and inaccurate GFR calculations caused by background activity.
Area of Science:
- Nuclear medicine
- Radiopharmacology
- Urology
Background:
- Augmented bladders present unique challenges in nuclear medicine imaging.
- Background activity from pertechnetate can lead to diagnostic errors.
Purpose of the Study:
- To compare bladder absorption of Tc-99m pertechnetate and Tc-99m sulfur colloid.
- To recommend optimal radiopharmaceutical use in augmented bladders.
Main Methods:
- Retrospective review of imaging studies.
- Comparison of radiotracer absorption characteristics in augmented bladders.
Main Results:
- Tc-99m sulfur colloid demonstrates less bladder absorption compared to pertechnetate.
- Reduced background activity observed with Tc-99m sulfur colloid.
Conclusions:
- Routine use of Tc-99m sulfur colloid is advised for augmented bladder imaging.
- This prevents misdiagnosis of vesicoureteral reflux and GFR miscalculation.