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Mobile app-based quantitative scanometric analysis.

Jessica X H Wong1, Frank S F Liu, Hua-Zhong Yu

  • 1Department of Chemistry and ‡Department of Molecular Biology and Biochemistry, Simon Fraser University , Burnaby, British Columbia V5A 1S6, Canada.

Analytical Chemistry
|November 25, 2014
PubMed
Summary
This summary is machine-generated.

Smartphones can now perform quantitative scanometric assays. A mobile app analyzes results, matching traditional scanners for accurate chemical analysis and medical diagnostics.

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Area of Science:

  • Analytical Chemistry
  • Mobile Health Technology

Background:

  • Scanometric assays are a method for quantitative chemical analysis.
  • Traditional detection platforms often require specialized equipment, limiting accessibility.

Purpose of the Study:

  • To demonstrate the feasibility of using smartphones as a platform for quantitative scanometric assays.
  • To develop and validate a mobile application for analyzing scanometric assay data.

Main Methods:

  • Comparison of different scanning modes (color, grayscale, black/white) and grayscale conversion protocols.
  • Development of a mobile application for imaging and analyzing scanometric assays.
  • Validation using paper-printed tests and a biotin-streptavidin assay.

Main Results:

  • The mobile app demonstrated comparable performance to traditional desktop scanners for optical darkness ratio (ODR) analysis.
  • Different scanning modes and protocols were evaluated for ODR determination.
  • Successful application on both paper and plastic substrates.

Conclusions:

  • Smartphones are a practical and accurate platform for quantitative chemical analysis.
  • Mobile devices can enhance accessibility for medical diagnostics and chemical testing.
  • The developed app provides a user-friendly solution for scanometric assay analysis.