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Published on: September 27, 2024
A new phenylpropanoid from the roots of Euphorbia nematocypha
Hai-Yang Jia1, Zhi-Xin Liao, Fu-Yue Liu
1a Department of Pharmaceutical Engineering , School of Chemistry and Chemical Engineering, Southeast University , Nanjing 211189 , PR China.
Abstract:
A phytochemical investigation of the ethanolic extracts of the dried roots of Euphorbia nematocypha resulted in the isolation of a new phenylpropanoid, 16-O-caffeoyl-16-hydroxylhexadecanoic acid (1), together with 23 known compounds (2-24). Their structures were elucidated on the basis of spectroscopic data. Compound 1 was first to be isolated as a caffeic acyl long chain alkyl acid from the family Euphorbiaceae. The new isolated phenylpropanoid showed potent cytotoxic activities against the MCF-7 and HeLa cell lines.
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