Related Experiment Video
Updated: Apr 20, 2026

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
Published on: September 18, 2020
Specific type epigenetic changes in cervical cancers
1Department of Gynecology, Qindao University School of Medicine, #16 Jiangsu Road, Shinan Qu, Qingdao, People's Republic of China, shuping.zhao@yahoo.com.
Abstract:
Cancer is a genetic and epigenetic disease. Multiple genetic and epigenetic changes have been studied in cervical cancer; however, such changes are selected for during tumorigenesis and tumor aggression is not yet clear. Cervical cancer is a multistep process with accumulation of genetic and epigenetic alterations in regulatory genes, leading to activation of oncogenes and inactivation or loss of tumor suppressor genes. In cervical cancer, epigenetic alterations can affect the expression of papillomaviral as well as host genes in relation to stages representing the multistep process of carcinogenesis.
Related Concept Videos
Epigenetic Regulation
X-chromosome...
Epigenetic Regulation
Inheritance of Chromatin Structures
Cellular Adaptation IV: Dysplasia and Metaplasia
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Chromatin Modification in iPS Cells
Compact chromatin makes reprogramming difficult. Enzymes, such as histone demethylases and acetyltransferases, are often added during reprogramming to loosen the chromatin, making the DNA more accessible to transcription factors. Molecules that inhibit histone...

