Related Experiment Video
Updated: Apr 20, 2026
06:41
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
13.2K
Recirculation in venovenous extracorporeal membrane oxygenation
Darryl Abrams1, Matthew Bacchetta, Daniel Brodie
1From the *Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York; and †Division of Thoracic Surgery, Department of Surgery, Columbia University College of Physicians & Surgeons, New York, New York.
ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|November 26, 2014
Summary
Recirculation reduces the effectiveness of venovenous extracorporeal membrane oxygenation (ECMO) oxygen delivery. Strategies like dual-lumen cannulae can minimize recirculation and improve ECMO efficiency when oxygenation is insufficient.
Area of Science:
- Cardiovascular Science
- Respiratory Physiology
- Medical Technology
Background:
- Venovenous extracorporeal membrane oxygenation (ECMO) is crucial for respiratory support.
- Recirculation, where oxygenated blood returns to the drainage cannula without systemic circulation, impairs ECMO efficiency.
- Quantifying and mitigating recirculation is essential for optimizing patient outcomes.
Purpose of the Study:
- To provide a comprehensive overview of recirculation in venovenous ECMO.
- To discuss factors influencing recirculation.
- To present methods for quantifying and reducing recirculation to enhance ECMO efficacy.
Main Methods:
- Literature review of factors affecting recirculation.
- Analysis of techniques for quantifying recirculation.
- Evaluation of interventions to minimize recirculation, including dual-lumen cannulae.
Main Results:
- Recirculation significantly decreases oxygen delivery during venovenous ECMO.
- Accurate quantification of recirculation can be challenging.
- Various strategies, notably dual-lumen cannulae, can effectively reduce recirculation.
Conclusions:
- Minimizing recirculation is vital for maximizing venovenous ECMO efficiency.
- Understanding recirculation dynamics aids in optimizing oxygen delivery.
- Interventions targeting recirculation improve therapeutic outcomes in patients requiring ECMO.
Related Concept Videos
01:25Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
361
Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
361
01:26Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
388
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
388
01:04Venous Return
15.6K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
15.6K
01:30Continuous Renal Replacement Therapy
2.1K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
2.1K
01:30Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
1.0K
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
1.0K
01:24Hemodialysis II: Procedure and Complications
2.1K
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
2.1K