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Sarcomatous Components May Predict Prognosis in Patients with Pulmonary Pleomorphic Carcinoma
Tetsuzo Tagawa1, Junichi Morimoto1, Shigetoshi Yoshida1
1Department of General Thoracic Surgery, Chiba University, Chiba, Japan.
Objectives And Methods:
Pulmonary pleomorphic carcinoma often presents with clinically aggressive behavior. We retrospectively reviewed 16 patients who underwent surgery from 1999 to 2013.
Results:
Sarcomatous components included spindle cell type in six (38%) patients, giant cell type in three (19%) patients, and mixed cell type in seven (44%) patients. The 5-year overall survival rate was 40.6%. On univariate analysis, spindle cell type, pN0, and small tumor diameter were associated with better prognosis. The 5-year survival of six patients with spindle cell type was 83.3%.
Conclusions:
Despite the small sample size, we suggest that patients with spindle cell type may have favorable prognoses.
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