Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

Blood Typing

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...

Rh Blood Group

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.

The ABO Blood Group

The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reinvigorating Evidence-Based Practice.

Journal for nurses in professional development·2021

Same author

Use of 4MAT Learning Theory to Promote Better Skin Care During Radiation Therapy: An Evidence-Based Quality Improvement Project.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society·2016

Same author

A Prospective Six Sigma Quality Improvement Trial to Optimize Universal Screening for Genetic Syndrome Among Patients With Young-Onset Colorectal Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN·2015

Same author

Promoting adherence to skin care practices among patients receiving radiation therapy.

Clinical journal of oncology nursing·2015

Same author

Quality of life as a predictor of weight loss in obese, early-stage breast cancer survivors.

Oncology nursing forum·2007

Same author

Predicting early academic achievement in a baccalaureate nursing program.

Journal of professional nursing : official journal of the American Association of Colleges of Nursing·2007

Search research articles

Related Experiment Video

Updated: Apr 20, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Changing blood transfusion policy and practice.

Catherine Stupnyckyj¹, Sheryl Smolarek, Colleen Reeves

¹Catherine Stupnyckyj and Sheryl Smolarek are clinical nurse leaders at the Barbara Ann Karmanos Cancer Institute, Detroit, where Colleen Reeves is a clinical nurse, Judith McKeith is a clinical nurse manager, and Morris Magnan is a clinical nurse specialist. Contact author: Morris Magnan, magnanm@karmanos.org. The authors have disclosed no potential conflicts of interest, financial or otherwise.

The American Journal of Nursing

|November 26, 2014

Summary

A small catheter (smaller than 20-gauge) can safely transfuse blood in adults, challenging the traditional practice. This evidence-based project led to a policy change, improving patient care during blood transfusions.

More Related Videos

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

Routine Screening Method for Microparticles in Platelet Transfusions

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

Related Experiment Videos

Last Updated: Apr 20, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

Routine Screening Method for Microparticles in Platelet Transfusions

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

Area of Science:

Nursing Practice
Evidence-Based Medicine
Patient Safety

Background:

Traditionally, a 20-gauge or larger catheter is recommended for adult blood transfusions, but supporting evidence is lacking.
Oncology nurses initiated an evidence-based practice project to investigate this standard practice.

Observation:

A literature search was conducted to evaluate the evidence for catheter size in blood transfusions.
Consultation with the American Association of Blood Banks and Infusion Nurses Society standards was performed.

Findings:

A catheter smaller than 20-gauge can be safely used for adult blood transfusions.
The evidence does not support the mandatory use of larger-gauge catheters for transfusion.

Implications:

The findings support a change in institutional policy regarding catheter size for blood transfusions.
This evidence-based practice change can enhance patient comfort and potentially reduce healthcare costs.
Promotes a culture of inquiry and evidence-based practice within nursing.