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Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock

Filip Jaśkiewicz1, Karolina Supeł, Włodzimierz Koniarek

  • 1Intensive Cardiac Therapy Clinic, Medical University of Lodz Łódź. cparamedikus@gmail.com.

Cardiology Journal
|November 28, 2014
PubMed

Insights

Hyperglycemia on admission is common in acute coronary syndrome (ACS) patients with cardiogenic shock (CS). However, this study found no link between high blood glucose and in-hospital death in these patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Critical Care Medicine

Background:

  • Increased admission blood glucose (ABG) is linked to adverse outcomes in acute coronary syndrome (ACS).
  • Hyperglycemia is an unfavorable prognostic factor in ACS patients with cardiogenic shock (CS).

Purpose of the Study:

  • To determine if admission hyperglycemia predicts in-hospital death in ACS patients with CS.

Main Methods:

  • Retrospective study of 40 patients with ACS and CS treated with primary percutaneous coronary intervention.
  • Control group of patients with uncomplicated ACS.

Main Results:

  • Patients with CS had significantly higher ABG levels compared to controls (15.4 vs. 7.97 mmol/L).
  • No significant correlation was found between ABG levels and in-hospital mortality.
  • Average ABG levels were similar in survivors and non-survivors (15.42 vs. 15.40 mmol/L).

Conclusions:

  • Admission hyperglycemia is a clinical feature of ACS patients who develop CS.
  • The prognostic value of admission hyperglycemia for in-hospital mortality in this population requires further investigation.
Abstract

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