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Heart Failure IV: Classification and Diagnostic Evaluation

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Related Experiment Video

Updated: Apr 20, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

A new score system for predicting response to cardiac resynchronization therapy.

Yu Kang, Leilei Cheng, Jie Cui

¹Department of echocardiography, Zhongshan hospital of Fudan university, Shanghai institute of cardiovascular disease, Shanghai, China. shu.xianhong@zs-hospital.sh.cn.

Cardiology Journal

|November 28, 2014

Summary

A new score system using echocardiography and ECG can effectively select patients for cardiac resynchronization therapy (CRT). This tool improves prediction of positive CRT response, aiding clinical decision-making.

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Published on: May 22, 2018

Area of Science:

Cardiology
Medical Devices
Biomedical Engineering

Background:

Cardiac resynchronization therapy (CRT) is a treatment for heart failure.
Selecting appropriate patients for CRT is crucial for treatment success.
Current patient selection methods may have limitations.

Purpose of the Study:

To develop a novel score system for CRT patient selection.
To integrate clinical, echocardiographic, and electrocardiographic data.
To evaluate the clinical utility of this score system.

Main Methods:

Ninety-three patients undergoing CRT were analyzed.
A score system was derived using Cox regression models.
Positive CRT response was defined by specific echocardiographic and clinical endpoints.

Main Results:

A 4-point score system was created using TAPSE, LS, CLBBB, and QRSd.
The score demonstrated high sensitivity (0.823) and specificity (0.850) for predicting CRT response.
The area under the curve (AUC) was 0.923, indicating strong predictive accuracy.

Conclusions:

The developed score system effectively predicts positive CRT response.
Integration of TAPSE, LS, CLBBB, and QRSd offers reliable patient selection.
This score can enhance clinical decision-making for CRT.