Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dynamic Equilibrium02:20

Dynamic Equilibrium

67.9K
A reversible chemical reaction represents a chemical process that proceeds in both forward (left to right) and reverse (right to left) directions. When the rates of the forward and reverse reactions are equal, the concentrations of the reactant and product species remain constant over time and the system is at equilibrium. A special double arrow is used to emphasize the reversible nature of the reaction. The relative concentrations of reactants and products in equilibrium systems vary greatly;...
67.9K
Distribution and Dispersion00:54

Distribution and Dispersion

26.2K
To understand intra-specific interactions in populations, scientists measure the spatial arrangement of species individuals. This geographic arrangement is known as the species distribution or dispersion. Highly territorial species exhibit a uniform distribution pattern, in which individuals are spaced at relatively equal distances from one another. Species that are highly tied to particular resources, such as food or shelter, tend to concentrate around those resources, and thus exhibit a...
26.2K
Homogeneous Equilibria for Gaseous Reactions02:15

Homogeneous Equilibria for Gaseous Reactions

30.9K
Homogeneous Equilibria for Gaseous Reactions
For gas-phase reactions, the equilibrium constant may be expressed in terms of either the molar concentrations (Kc) or partial pressures (Kp) of the reactants and products. A relation between these two K values may be simply derived from the ideal gas equation and the definition of molarity. According to the ideal gas equation:
30.9K
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

5.7K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
5.7K
Diffusion01:21

Diffusion

7.4K
Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
7.4K
Diffusion01:12

Diffusion

232.4K
Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
232.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A brief overview of 20 years of neuroscience in PLoS Computational Biology.

PLoS computational biology·2026
Same author

Transient pores account for cell-penetrating peptide and homeoprotein translocation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Vascular segmentation of functional ultrasound images using deep learning.

Computers in biology and medicine·2025
Same author

Enhancing fluorescence correlation spectroscopy with machine learning to infer anomalous molecular motion.

Biophysical journal·2025
Same author

A coupled neural field model for the standard consolidation theory.

Journal of theoretical biology·2024
Same author

Serum Versus Fecal Calprotectin Levels in Patients with Severe Obesity Before and 6 Months After Roux-Y-Gastric Bypass: Report of the Prospective Leaky-Gut Study.

Obesity surgery·2023
Same journal

What role does the Notch signaling pathway play in exercise-related metabolic and neurological adaptations? A molecular-to-systems perspective.

Frontiers in physiology·2026
Same journal

Variation in skin barrier function throughout smoltification in Atlantic salmon (<i>Salmo salar</i>).

Frontiers in physiology·2026
Same journal

Correction: What role does the Notch signaling pathway play in exercise-related metabolic and neurological adaptations? A molecular-to-systems perspective.

Frontiers in physiology·2026
Same journal

Effect of high intensity interval Nordic walking and strength training on selected biomarkers of metabolic syndrome in postmenopausal women with abdominal obesity: a quasi-experimental studies.

Frontiers in physiology·2026
Same journal

The interplay between sexual activity, athletic performance, and recovery in athletes: a narrative review.

Frontiers in physiology·2026
Same journal

The alveolar edema equation.

Frontiers in physiology·2026
See all related articles

Related Experiment Video

Updated: Apr 20, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

9.2K

Spatial distributions at equilibrium under heterogeneous transient subdiffusion.

Hugues Berry1, Hédi A Soula2

  • 1Beagle, Institut National de Recherche en Informatique et en Automatique Villeurbanne, France ; Laboratoire d'InfoRmatique en Image et Systèmes d'information, UMR 5205 CNRS-INSA, Université de Lyon Villeurbanne, France.

Frontiers in Physiology
|November 28, 2014
PubMed
Summary
This summary is machine-generated.

Proteins in cells exhibit transient subdiffusion. Restricted subdiffusion in a specific region leads to non-homogeneous protein accumulation, driven by the long-term Brownian motion, not initial dynamics.

Keywords:
brownian diffusioncontinuous-time random walksnonhomogeneous cellular mediaspatial protein distributionsubdiffusion

More Related Videos

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
06:55

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Published on: September 26, 2016

8.6K
Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.8K

Related Experiment Videos

Last Updated: Apr 20, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

9.2K
Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
06:55

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Published on: September 26, 2016

8.6K
Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.8K

Area of Science:

  • Biophysics
  • Cellular Dynamics
  • Statistical Mechanics

Background:

  • Macromolecule mobility in cells, particularly proteins, often shows transient subdiffusion.
  • The spatial distribution of proteins during subdiffusion confined to specific cellular regions remains poorly understood.

Purpose of the Study:

  • To investigate the equilibrium spatial distribution of proteins exhibiting transient subdiffusion within a restricted spatial region.
  • To explore the influence of continuous-time random walks (CTRW) on protein spatial distribution under confinement.

Main Methods:

  • Utilized Monte Carlo simulations to model protein dynamics.
  • Analyzed the spatial distribution of proteins undergoing transient subdiffusion in a 2D space with a restricted subregion.

Main Results:

  • Simulations revealed a non-homogeneous spatial distribution of proteins at equilibrium.
  • Protein accumulation in the CTRW subregion increased with the degree of anomalous properties.
  • For transient CTRW, accumulation was governed by the asymptotic Brownian regime, not initial transient dynamics.

Conclusions:

  • Transient subdiffusion confined to a subregion leads to non-homogeneous protein distribution at equilibrium.
  • The asymptotic Brownian regime significantly influences protein accumulation in CTRW scenarios.
  • Different subdiffusion models can result in distinct spatial protein distributions, even with similar mean-squared displacement behavior.