Related Experiment Video
Updated: Apr 20, 2026

09:01
Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
Published on: March 16, 2011
31.4K
A bacterial mutant library as a tool to study the attack of a defensin peptide
Simone Moser1, Haritha R Chileveru, Jill Tomaras
1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA).
Chembiochem : a European Journal of Chemical Biology
|November 29, 2014
Abstract:
Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

