Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders:
Jan Sundquist1, Åsa Lilja1, Karolina Palmér1
1Jan Sundquist, MD, PhD, Center for Primary Health Care Research, Lund University, Malmö, Sweden and Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, California, USA;Åsa Lilja, PhD, Karolina Palmér, Msci, Ashfaque A. Memon, MD, PhD, Xiao Wang, MD, PhD, Leena Maria Johansson, MD, PhD, Center for Primary Health Care Research, Lund University, Malmö, Sweden; Kristina Sundquist, MD, PhD, Center for Primary Health Care Research, Lund University, Malmö, Sweden and Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, California, USA.
Background:
Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive.
Aims:
The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders.
Method:
This 8-week RCT (ClinicalTrials.gov ID: NCT01476371) was conducted during spring 2012 at 16 general practices in Southern Sweden. Eligible patients (aged 20-64 years) scored ≥10 on the Patient Health Questionnaire-9, ≥7 on the Hospital Anxiety and Depression Scale or 13-34 on the Montgomery-Åsberg Depression Rating Scale (self-rated version). The power calculations were based on non-inferiority. In total, 215 patients were randomised. Ordinal mixed models were used for the analysis.
Results:
For all scales and in both groups, the scores decreased significantly. There were no significant differences between the mindfulness and control groups.
Conclusions:
Mindfulness-based group therapy was non-inferior to treatment as usual for patients with depressive, anxiety or stress and adjustment disorders.
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