Related Experiment Video
Updated: Apr 20, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Sickle cell trait: not as benign as once thought.
Uqba Khan1, Lauren Kleess2, Justin Yeh2
1Department of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USA; uqba.md@gmail.com.
Sickle cell trait can cause renal papillary necrosis, a serious kidney condition. Prompt diagnosis and differentiation from renal medullary carcinoma are crucial for patient outcomes.
Area of Science:
- Nephrology
- Hematology
- Radiology
Background:
- Sickle cell trait is often misperceived as benign.
- It is associated with significant renal morbidity, including renal papillary necrosis and renal medullary carcinoma.
- Renal papillary necrosis requires prompt diagnosis and differentiation from renal medullary carcinoma due to potentially fatal consequences.
More Related Videos
08:23Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
05:23Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Related Concept Videos
Multiple Allele Traits
Multiple Allele Traits
Pedigree Analysis
X-linked Traits
X-linked Traits
Incomplete Dominance