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Comparison between intra- and extracellular surfactant in respiratory distress induced by oleic acid
C Casals1, L Herrera, E Miguel
1Department of Biochemistry, Faculty of Chemistry, Universidad Complutense, Madrid, Spain.
Biochimica Et Biophysica Acta
|June 8, 1989
Abstract:
The present study compares the phospholipid distribution and protein content in bronchoalveolar lavage, purified extracellular surfactant and lamellar bodies isolated from rabbits killed at intervals of 2.5, 12 and 24 h after oleic acid administration. The data suggest that the alteration of pulmonary surfactant could be partially due to the type II cell response to the injury.