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Updated: Apr 20, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Eye shape using partial coherence interferometry, autorefraction, and SD-OCT.

Christopher A Clark¹, Ann E Elsner, Benjamin J Konynenbelt

¹*OD †PhD, FAAO ‡BS Indiana University School of Optometry, Bloomington, Indiana (all authors).

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|December 2, 2014

Summary

This summary is machine-generated.

Spectral domain optical coherence tomography (SD-OCT) offers a more accurate method for measuring retinal shape than autorefraction. This technique reveals differences in curvature between myopes and others, closer to the fovea than previously understood.

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Published on: August 4, 2018

Area of Science:

Ophthalmology
Optometry
Vision Science

Background:

Peripheral refraction and retinal shape are crucial factors in refractive development.
Peripheral refraction measurements can be variable and time-consuming.
Emerging technologies like spectral domain optical coherence tomography (SD-OCT) offer potential for more reliable assessments.

Purpose of the Study:

To compare the reliability of SD-OCT and peripheral axial length measurements against traditional autorefraction for assessing retinal shape.
To investigate the relationship between retinal shape and refractive error (myopia, emmetropia, hyperopia).

Main Methods:

Seventy-nine subjects (ages 22-34) underwent imaging using 30-degree SD-OCT in a radial pattern.
Peripheral refraction was measured using an autorefractor, and peripheral axial length was measured with partial coherence interferometry.
Statistical analyses included repeated-measures ANOVA, Bland-Altman analyses, and regression, with all measures converted to diopters for comparison.

Main Results:

SD-OCT revealed increased retinal curvature in myopes compared to emmetropes/hyperopes, with significant changes noted around 5 degrees.
SD-OCT provided a retinal shape resolution of 0.026 diopters, approximately 10 times more accurate than autorefraction.
Bland-Altman analyses indicated greater consistency between SD-OCT and partial coherence interferometry measurements than with autorefraction.

Conclusions:

SD-OCT provides highly accurate retinal shape measurements, revealing differences between refractive groups closer to the fovea.
Retinal shape appears to be influenced by central refractive error, challenging the notion that peripheral optics are solely responsible.
SD-OCT and partial coherence interferometry are more consistent and potentially more accurate than autorefraction for evaluating retinal shape.