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Mild cognitive dysfunction does not affect diabetes mellitus control in minority elderly adults
Priya Palta1, Sherita H Golden, Jeanne Teresi
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Journal of the American Geriatrics Society
|December 3, 2014
Summary
Mild cognitive dysfunction in older adults with type 2 diabetes mellitus did not significantly impact key metabolic control markers like glycosylated hemoglobin, blood pressure, or cholesterol levels over two years.
Area of Science:
- Gerontology
- Endocrinology
- Neuroscience
Background:
- Older adults with type 2 diabetes mellitus (T2DM) are at risk for cognitive dysfunction.
- Cognitive impairment may affect self-management of chronic conditions, potentially impacting metabolic control.
Purpose of the Study:
- To investigate the association between cognitive dysfunction (executive and memory) and metabolic control in older adults with T2DM.
- To compare glycosylated hemoglobin (HbA1c), systolic blood pressure (SBP), and low-density lipoprotein cholesterol (LDL-C) levels in T2DM patients with and without cognitive dysfunction.
Main Methods:
- Prospective cohort study of 613 older adults (mean age 73) with T2DM in New York City.
- Participants classified with executive or memory dysfunction using standardized cognitive tests.
- Linear mixed models analyzed repeated measures of HbA1c, SBP, and LDL-C over a median of 2 years.
Main Results:
- 54% had executive dysfunction, 33% had memory dysfunction, and 16% had both.
- No significant differences in metabolic control (HbA1c, SBP, LDL-C) were observed between participants with and without cognitive dysfunction.
- The rate of change in metabolic parameters did not differ significantly based on cognitive status.
Conclusions:
- Mild cognitive dysfunction does not appear to significantly impair metabolic control in older adults with T2DM.
- Caregiver support may mitigate the impact of cognitive impairment on diabetes management.
- More severe cognitive dysfunction might still affect diabetes control parameters.
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