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Related Experiment Video

Updated: Apr 20, 2026

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology

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Published on: May 31, 2024

[Glaucoma medications, preservatives and the ocular surface.]

F Aptel¹, A Labbé², C Baudouin²

¹Centre hospitalier universitaire, boulevard de la Chantourne, 38700 La Tronche, France.

Journal Francais D'Ophtalmologie

|December 3, 2014

Summary

Glaucoma eye drops often cause ocular surface disease due to preservatives. Reducing preservative exposure is key, rather than masking side effects with more drops.

Keywords:

Benzalkonium chloride Chlorure de benzalkonium Collyres Conservateurs Dry eye Eye drop Glaucoma Glaucome Medications Ocular surface Preservative Surface oculaire Sécheresse oculaire Tolerability Tolérance Toxicity Toxicité Traitement

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Last Updated: Apr 20, 2026

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Ultrasound Cyclo Plasty in Eyes with Glaucoma

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Published on: January 26, 2018

Area of Science:

Ophthalmology
Ocular Surface Disease
Glaucoma Management

Background:

Ocular surface disease is prevalent in patients undergoing chronic glaucoma treatment.
Preservatives in glaucoma medications are a significant factor contributing to ocular surface disease.
These surface changes manifest as patient symptoms and clinical signs in the anterior segment.

Approach:

Systematic assessment of ocular surface health is crucial for all glaucoma patients.
Evaluate patient history and clinical examination findings for ocular surface disease.
Focus on minimizing preservative exposure in glaucoma patients with ocular surface disease.

Key Points:

Chronic glaucoma drops frequently lead to ocular surface disease.
Preservatives in eye drops are a primary cause of these adverse ocular surface changes.
Ocular surface disease presents with both subjective symptoms and objective clinical signs.

Conclusions:

Management of glaucoma patients with ocular surface disease requires a shift in strategy.
Prioritize reducing preservative load rather than adding more medications.
Addressing the root cause (preservatives) is more effective than managing symptoms.