[Endovascular therapy in the treatment of acute ischemic stroke: what the cardiologist should know]
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Updated: Apr 20, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
G Vellieux1, S Evrard1, P Guedin2
1Unité de neurovasculaire, service de neurologie, hôpital Foch, université Versailles - Saint-Quentin-en-Yvelines, 40, rue Worth, 92150 Suresnes, France.
Insights
Mechanical thrombectomy offers a vital alternative for ischemic stroke patients ineligible for IV fibrinolysis. This endovascular procedure effectively recanalizes cerebral occlusions, improving clinical outcomes in critical situations.
Area of Science:
- Neurology
- Interventional Cardiology
- Neuroradiology
Background:
- Ischemic stroke complications frequently occur during interventional cardiology procedures.
- Intravenous fibrinolysis, the standard treatment, is often contraindicated in these patients.
- Interventional neuroradiology has developed mechanical thrombectomy techniques to address this gap.
Observation:
- Two cases of ischemic stroke during cardiovascular procedures with contraindications to IV fibrinolysis were treated.
- Patients presented with contraindications including anticoagulation for atrial fibrillation and recent carotid surgery.
- Endovascular thrombectomy was successfully employed in both emergency cases.
Findings:
- Mechanical thrombectomy is an effective alternative or complementary treatment to IV fibrinolysis for ischemic stroke.
- Endovascular thrombectomy devices enable recanalization of proximal cerebral occlusions.
- Successful recanalization correlates with a favorable clinical prognosis.
Implications:
- A "thrombolysis alert" system is crucial for rapid diagnosis and treatment selection in stroke patients during cardiovascular procedures.
- Mechanical thrombectomy expands treatment options for stroke patients with contraindications to fibrinolysis.
- Ongoing advancements in endovascular techniques and patient selection are improving stroke management.
Introduction:
Interventional cardiology procedures are regularly exposed to ischemic neurological complications. IV fibrinolysis is the only approved treatment in ischemic stroke but is very often contraindicated in these situations. Many techniques of interventional neuroradiology (mechanical thrombectomy) have been developed over the past years and are used to treat these patients.
Observation:
We report the case of two patients who were admitted in emergency for ischemic stroke with contraindication to IV fibrinolysis (cardioversion for atrial fibrillation under anticoagulation; 24 hours after carotid surgery). These patients were treated by endovascular thrombectomy procedure.
Discussion:
After validation of IV fibrinolysis within 4.5 hours after stroke onset, techniques of mechanical thrombectomy have gradually been developed, either as a complementary treatment or as an alternative in the case of CI to fibrinolysis. These endovascular thrombectomy devices currently allow recanalization of proximal cerebral occlusions, which correlates with a favorable clinical prognosis. A review of the literature is provided, along with a discussion about the techniques currently being improved, their advantages and disadvantages and the selection of patients that can benefit from endovascular procedures.
Conclusion:
In the case of a sudden occurrence of a neurological deficit during a cardiovascular procedure, a "thrombolysis alert" should be triggered. This will permit the rapid establishment of a clinico-radiological report for selecting stroke patients eligible for a procedure of recanalization by thrombolysis and/or mechanical thrombectomy.
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