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Updated: Apr 20, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Should pyogenic granulomas following burns be excised?
Hongliang Zhao1, Sha Huang2, Xiaobing Fu3
1General Hospital of PLA, Trauma Center of Postgraduate Medical College , 28 Fu Xing Road, Beijing 100853, PR China.
Pyogenic granuloma following burns (PGB) presents unique clinical and histological features. Conservative management is recommended initially for PGB, with surgery reserved for refractory cases.
Area of Science:
- Dermatology
- Plastic Surgery
- Burn Management
Background:
- Pyogenic granuloma following burns (PGB) exhibits distinct clinical manifestations compared to classic pyogenic granuloma.
- Understanding these differences is crucial for appropriate patient management.
Purpose of the Study:
- To review the literature on pyogenic granuloma following burns (PGB).
- To discuss the necessity of surgical excision for PGB.
- To analyze the clinical and histological features of PGB.
Main Methods:
- A comprehensive literature search was conducted using PubMed, EMBASE, Cochrane Library, and Web of Science databases.
- Included studies focused on the diagnosis and treatment of PGB with histological confirmation.
- Articles published in English between 1978 and 2013 were analyzed.
Main Results:
- PGB typically erupts 1-4 weeks post-burn in the affected area, potentially with superimposed infections.
- Histological findings include hyperkeratosis, acanthosis, proliferative vasculature, and inflammatory cell infiltration.
- Spontaneous involution and conservative management showed no recurrence in several cases.
Conclusions:
- Pyogenic granuloma following burns (PGB) is a benign condition based on clinical and histological evidence.
- PGB progresses through proliferative and shrivelling stages.
- Conservative treatment, including wound care and antibiotics, should be the first-line approach, with surgery considered if conservative measures fail.
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