Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleiotropy01:33

Pleiotropy

44.4K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
44.4K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.3K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.3K
Acne Infection01:27

Acne Infection

78
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
78
Skin Cancer01:30

Skin Cancer

6.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.7K
Prosopagnosia01:24

Prosopagnosia

1.2K
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
1.2K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

5.9K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visual recognition and medical dermatology learning needs identified through continuing certification program assessments of the American Board of Dermatology.

Journal of the American Academy of Dermatology·2026
Same author

Pediatric Dermatology Learning Needs Identified Through Continuing Certification Program Assessments of the American Board of Dermatology.

Pediatric dermatology·2025
Same author

Dermatopathology Learning Needs Identified Through Continuing Certification Program Assessments of the American Board of Dermatology.

Journal of cutaneous pathology·2025
Same author

Cosmetic and Surgical Dermatology Learning Needs Identified Through Continuing Certification Program Assessments of the American Board of Dermatology.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2025
Same author

Letter from the journal: Improving diagnostic acumen and patient outcomes.

Journal of the American Academy of Dermatology·2023
Same author

Pigmentary mosaicism.

Clinics in dermatology·2022
Same journal

Letter to the editor in reply to "Ethics of Rising Trends in Dermatology Publications Using Large-Scale Databases".

Clinics in dermatology·2026
Same journal

Ethics of suggesting image-guided superficial radiation therapy on the pathology report.

Clinics in dermatology·2026
Same journal

Tanorexia: The Psychodermatology of Compulsive Tanning.

Clinics in dermatology·2026
Same journal

Ear manifestations of connective tissue diseases: A dermatologic, histopathologic, and clinicopathologic review.

Clinics in dermatology·2026
Same journal

Discovery of an intravenous drug injection site: A meticulous cutaneous examination provides the forensic dermatologic clue to a diagnosis of homicide.

Clinics in dermatology·2026
Same journal

Sherlock Holmes and the mystery of the deadly diet.

Clinics in dermatology·2026
See all related articles

Related Experiment Video

Updated: Apr 20, 2026

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
10:23

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans

Published on: September 8, 2023

4.0K

Facial involvement in genodermatoses.

Julie V Schaffer1

  • 1Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, 11th Floor, New York, NY 10016, USA.

Clinics in Dermatology
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

Facial findings in genodermatoses (genetic skin diseases) are key diagnostic clues. Recognizing these patterns aids in early diagnosis, management, and treatment of associated conditions.

More Related Videos

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

927
Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
09:25

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development

Published on: March 24, 2011

10.0K

Related Experiment Videos

Last Updated: Apr 20, 2026

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
10:23

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans

Published on: September 8, 2023

4.0K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

927
Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
09:25

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development

Published on: March 24, 2011

10.0K

Area of Science:

  • Dermatology
  • Genetics
  • Medical Diagnostics

Background:

  • Facial manifestations are common in genodermatoses.
  • Visible facial lesions can cause significant patient distress and stigmatization.
  • Accurate diagnosis is crucial for effective management and genetic counseling.

Purpose of the Study:

  • To categorize facial involvement in genodermatoses based on morphology.
  • To provide a practical clinical approach for identifying genetic skin conditions.
  • To highlight the importance of facial findings in diagnosis and management.

Main Methods:

  • Classification of facial genodermatoses into five morphologic categories.
  • Review of characteristic facial features associated with genetic skin disorders.
  • Clinical observation and diagnostic correlation.

Main Results:

  • Facial involvement in genodermatoses can be categorized into: papules, scaling, photosensitivity/aging findings, blisters/erosions, and birthmarks.
  • Specific facial features aid in diagnosing genodermatoses.
  • Identification of extracutaneous manifestations is improved by recognizing facial patterns.

Conclusions:

  • A morphologic classification system for facial genodermatoses offers a practical diagnostic tool.
  • Awareness of facial findings is critical for dermatologists in managing genetic skin diseases.
  • Early recognition of facial signs facilitates timely treatment and improves patient outcomes.